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    Available online at
    Original Research
    Association of clinical outcomes in metastatic breast cancer patients with circulating tumour cell and circulating cell-free DNA
    Zhong Ye a,1, Chun Wang a,1, Shaogui Wan b,1, Zhaomei Mu c, Zhenchao Zhang a, Maysa M. Abu-Khalaf a, Frederick M. Fellin a, Daniel P. Silver a, Manish Neupane a, Rebecca J. Jaslow a,
    Saveri Bhattacharya a, Theodore N. Tsangaris a, Inna Chervoneva d, Adam Berger e, Laura Austin a, Juan P. Palazzo f, Ronald E. Myers a, Neha Pancholy a, Darayus Toorkey a, Kaelan Yao a, Max Krall a, Xiuling Li g, Xiaobing Chen h, Xiuhong Fu i, Jinliang Xing j, Lifang Hou k, Qiang Wei l, Bingshan Li l, Massimo Cristofanilli c,**, Hushan Yang a,*
    a Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    b Institute of Pharmacy, Pharmaceutical College, Henan University, Kaifeng, Henan 475004, China
    c Department of Medicine, Division of Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA d Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA