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br Unantimycin A has a
2020-08-07
Unantimycin A has a chemical structure similar to that of SW-163A, which is in the neoantimycin class of compounds. Neoantimycin and antimycin A are best known to inhibit complex III by specifically binding to the quinone reduction site (Qi) of this complex, thus blocking electron transfer from he
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br Results br On bivariate analysis
2020-08-06
3. Results On bivariate analysis, significant differences were noted across BMI categories in age at diagnosis, histology, stage, race, grade, hyperten-sion, hyperlipidemia, diabetes, and treatment modalities (Table 1). Overall, there was a significant inverse linear association of age at diag-
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Norfloxacin br Krieger N Overcoming the
2020-08-06
8. Krieger N. Overcoming the absence of socioeconomic data in medical records: validation and application of Norfloxacin census-based methodology. Am J Public Health 1992; 82:703-10. 9. Krieger N, Chen JT, Waterman PD, Rehkopf DH, Subramanian SV. Painting a truer picture of US socioeconomic and
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Elsevier Inc All rights reserved br Introduction
2020-08-06
© 2019 Elsevier Inc. All rights reserved. 1. Introduction Established risk factors for cancer include obesity, physical inactivity, smoking, and alcohol use [1–4]. These risk factors are associated with chronic Paxilline and metabolic dysregulation, and growing evi-dence links these mechanism
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br S Morishita et al br size was small
2020-08-05
S. Morishita, et al. size was small. Thus, we did not show the effect of different cancer types on the relation between balance function and muscle strength. In future studies, we should present the possible mechanisms of balance function in cancer survivors with a larger sample size. 6. Concl
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br T weighted and dynamic contrast
2020-08-04
T2-weighted and dynamic contrast-enhanced magnetic resonance imaging (MRI) recently replaced computed tomography urography (CTU) for the differentiation be-tween NMIBC and MIBC [3]. Although imaging is not the gold standard to evaluate the invasiveness of BC, an MRI-based standardized reporting sy
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Dorsomorphin (Compound C) br JOURNAL br This intensity relat
2020-08-04
JOURNAL This intensity relates the ability of each tested cell line to produce the ROS responsible for the oxidation of the boron-carbon bond leading to the release of coumarin. Since oxidation and subsequent self-immolation of precursor 3 is rather slow and dependent of the ROS concentration,
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br F Li T Li W Cao
2020-08-02
[9] F. Li, T. Li, W. Cao, et al. Near-infrared light stimuli-responsive synergistic therapy nanoplatforms based on the coordination of tellurium-containing block polymer and cisplatin for cancer treatment. Biomaterials. 133 (2017) 208–218. [10] D. Yang, W. Luo, J. Wang, et al. A novel controlled
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br activate transcription of casein kinase and ER antagonist
2020-08-02
activate transcription of casein kinase 2 [69], and ER antagonists block this action. In general, MDSC are not present in healthy individuals but occur in pathologic states associated with chronic inflammation and cancer [17]. For example, BC biopsies from patients with residual disease after c
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br The release behavior of
2020-07-29
The release behavior of CSs from the CDEAC hydrogel upon adding the ClO− (10 nM) was further studied. MCF-7 RGX-104 did not show ob-vious toxicity when cultured with ClO−/SCN−(Supplementary Fig. S21). As shown in Fig. 6A, the morphology of the released CSs were identical to that of the prerelease
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br Cognitive mediation model br This study also
2020-07-29
1.1.2. Cognitive mediation model This study also employed the Cognitive Mediation Model as another conceptual framework to better explain the pathways linking OHIS to health literacy. Whereas the Health Literacy Skills Framework is useful in explaining factors (e.g., OHIS) contributing to the d
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BCI-121 br ACCEPTED MANUSCRIPT br compared with surgery alon
2020-07-28
ACCEPTED MANUSCRIPT 0.80-0.99) compared with surgery alone. In agreement with this BCI-121 meta-analysis, we found that patients receiving neoadjuvant therapy followed by esophagectomy had significantly improved long-term survival compared to patients undergoing esophagectomy alone. However, t
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br Introduction br The p protein produced from mRNA
2020-07-27
1. Introduction The p53 protein, produced from mRNA encoded by the TP53 gene, plays a perhaps more crucial role than any other tumor suppressor in preventing tumorigenesis and tumor progression. Moreover, p53 is an essential and powerful transcription factor, acting through the binding of it
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br The identity of RP MAP was confirmed by
2020-07-27
The identity of RP8-MAP4 was confirmed by its molecular ion peak in its mass spectrum (Fig. S1). The [Mþ6H]6þ, [Mþ7H]7þ, [Mþ8H]8þ and [Mþ9H]9þ ions were indicative of its presence. The HPLC chromatogram indicated its purity was ~95.5% (Fig. S2). The result demonstrated that the retention time of t
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br of these studies have been
2020-07-26
of these studies have been extremely optimistic. This indubitably in-dicates the feasibility along with the ease of inclusion of quinolines as a flexible component in diverse antitumor pharmacophores. Moreover, quinoline-based HSP90 inhibitors have also demonstrated efficacy in some recently co